Key result
Brain infarction was associated with significantly impaired heart rate responses to autonomic testing in the acute phase compared to healthy controls (P<.05), indicating parasympathetic hypofunction.
Why the study?
Does brain infarction cause parasympathetic hypofunction as measured by cardiovascular autonomic reflexes compared to healthy controls?
Population
40 patients with brain infarction and 55 healthy control subjects
Comparison
Measurement of cardiovascular autonomic reflexes… vs 55 healthy control subjects
Design
Cohort
Follow-up
6 months
Authors
Loading...
May indicate added autonomic risk post-stroke; leaves open prognostic value and need for prospective studies.
Observational (n=95)
Does brain infarction cause parasympathetic hypofunction as measured by cardiovascular autonomic reflexes compared to healthy controls?
p-value: p=<.05
Brain infarction causes parasympathetic hypofunction in the acute phase, which partially recovers over 6 months, contributing to cardiovascular autonomic disturbances.
Korpelainen et al. (1994) conducted an observational in Brain infarction (n=95). Brain infarction vs. Healthy control subjects was evaluated on Heart rate and blood pressure responses to normal and deep breathing, the Valsalva maneuver, tilting, and isometric work (p=<.05). Brain infarction was associated with significantly impaired heart rate responses to autonomic testing in the acute phase compared to healthy controls (P<.05), indicating parasympathetic hypofunction.