Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 1, 1996Acta Neurologica Scandinavica

Abnormal heart rate variability reflecting autonomic dysfunction in brainstem infarction

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does brainstem infarction impair heart rate variability compared to healthy controls?

Population

15 consecutive patients with brainstem infarction and 15 age- and sex-matched healthy control subjects

Comparison

Brainstem infarction (medullary and pontine) vs Age- and sex-matched healthy control subjects

Design

Cohort

Follow-up

6 months

Authors

JKJuha T. KorpelainenOulu University HospitalHHHeikki V. HuikuriElectrophysiologyKSK. A. SotaniemiOulu University Hospital

Discussion

Loading...

Member takes

Implication

Medullary infarction may transiently impair HRV and raise cardiac risk; leaves open whether autonomic monitoring improves stroke outcomes.

Structured PICO

Does brainstem infarction impair heart rate variability compared to healthy controls?

P
Population
15 consecutive patients with brainstem infarction and 15 age- and sex-matched healthy control subjects
I
Intervention
Brainstem infarction (medullary and pontine)
C
Comparator
Age- and sex-matched healthy control subjects
O
Outcome
Power spectrum of heart rate variability (total power, very-low-frequency power, low-frequency power, and high-frequency power) measured from 24-hour electrocardiogram in the acute phase and at 1 month and 6 monthssurrogate

Medullary brainstem infarction causes transient cardiovascular autonomic dysregulation manifesting as impaired heart rate variability in the acute phase, which may contribute to cardiac complications in stroke.

Cite This Study

Korpelainen et al. (1996) studied this question.

synapsesocial.com/papers/6a74eed2fc5fd65369f54236https://doi.org/10.1111/j.1600-0404.1996.tb07076.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impaired Low-Frequency Oscillations of Heart Rate in Patients With Prior Acute Myocardial Infarction and Life-Threatening Arrhythmias1995 · 79 citations
  2. 2Suppressed sympathetic skin response in brain infarction.1993 · 81 citations
  3. 3Decreased heart rate variability and its association with increased mortality after acute myocardial infarction1987 · 4,025 citations
  4. 4Heart rate variability in coronary artery disease1995 · 77 citations
  5. 5Sympathetic predominance an essential hypertension: a study employing spectral analysis of heart rate variability1988 · 419 citations