Why the study?
Does antibiotic prophylaxis reduce wound infection in patients undergoing appendicectomy?
Population
830 patients undergoing appendicectomy
Comparison
Antibiotic prophylaxis and treatment vs No antibiotic treatment (n=553)
Design
Cohort
Authors
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May support prophylaxis consideration in perforated appendicitis; leaves open randomized confirmation of benefit.
Does antibiotic prophylaxis reduce wound infection in patients undergoing appendicectomy?
Antibiotic prophylaxis is important in reducing wound infection rates in patients undergoing appendicectomy, particularly in cases of perforated appendicitis or when Bacteroides fragilis is isolated.
D. A. Leigh (1978) studied this question.
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