Why the study?
How does exercise affect the pressure-flow relationship in the pulmonary circulation of normal subjects compared to those with chronic bronchitis or mild mitral stenosis?
How does exercise affect the pressure-flow relationship in the pulmonary circulation of normal subjects compared to those with chronic bronchitis or mild mitral stenosis?
Exercise induces an inappropriate increase in pulmonary vascular resistance in patients with chronic bronchitis, unlike in normal subjects or those with mild mitral stenosis.
Exercise may provoke abnormal pulmonary vascular resistance in chronic bronchitis; leaves open clinical relevance pending prospective validation.
The relation between pressure and flow in the pulmonary circulation during recumbency appears to be virtually linear in normal people and in mild mitral stenosis but curved in chronic bronchitis. Exercise has no effect on this relation in the former two groups but causes an inappropriate increase in vascular resistance in chronic bronchitis.
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Harris et al. (1968) studied this question.
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