Population
16 patients with severe mitral stenosis
Design
Cross-sectional
Authors
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May limit lung biopsy utility for gauging resistance in mitral stenosis; leaves open reversible vasoconstriction as key mechanism.
Reversible vasoconstriction may play an important role in the pathogenesis of pulmonary hypertension associated with severe mitral stenosis, as structural abnormalities do not correlate with hemodynamic resistance.
Curti et al. (1953) studied this question.
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