Key result
Mitral stenosis causes an obstructive lesion that leads to a rise in pressure proximal to the obstruction and a reduction in cardiac output, with the normal adult mitral valve orifice being ~5 sq. cm.
Population
Patients with mitral stenosis
Design
Review
Authors
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Underpins mitral stenosis severity assessment; leaves open need for contemporary hemodynamic validation in diverse cohorts.
Describes the fundamental hemodynamic consequences of mitral stenosis, including proximal pressure elevation and reduced cardiac output.
Lewis Dexter (1956) conducted a review in Mitral Stenosis. Mitral stenosis causes an obstructive lesion that leads to a rise in pressure proximal to the obstruction and a reduction in cardiac output, with the normal adult mitral valve orifice being ~5 sq. cm.
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