Why the study?
Non-bacterial thrombotic endocarditis causes myocardial and cerebral infarctions in advanced malignancy, but only a few cases presenting with both infarctions in the same patient have been reported.
Highlights the importance of considering non-bacterial thrombotic endocarditis in patients with malignancies who present with life-threatening thromboembolism in multiple organs.
Highlights NBTE embolic risk in advanced gynecologic cancer; leaves open optimal screening and antithrombotic strategies.
Non-bacterial thrombotic endocarditis (NBTE) causes myocardial and cerebral infarctions and is associated with advanced stages of malignancy. However, only a few cases of myocardial and cerebral infarctions have been reported in the same patient. We herein report a 47-year-old woman with advanced uterine and ovarian cancer who experienced acute myocardial infarction (MI) after receiving chemotherapeutic intervention for the cancer and hemorrhagic cerebral infarction 1 month after admission for acute MI, attributable to NBTE of the aortic valve. NBTE should be considered in patients with malignancies and life-threatening thromboembolism of important organs.
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Hisata et al. (2024) studied this question.
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