Presents a case of complete congenital heart block with multilevel block.
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Case report suggests multilevel conduction disease in CHB; leaves open whether this alters prognosis or device strategy.
Congenital heart block (CHB) has long been associated with maternal anti-SSA/Ro antibodies. Injury to the conduction system is presumed to be a consequence of the transplacental passage of maternal IgG autoantibodies into the fetal circulation.1 Within the heart, a spectrum of phenotypes has been described, including structural defects, functional abnormalities, and electrical disturbances such as heart block. Third-degree atrioventricular (AV) block is typically irreversible, has a mortality rate approaching 30%, and requires pacemaker placement in up to 66% of cases.
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Hovis et al. (2017) studied this question.
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