INTRODUCTION 281 NATURALLY OCCURRING FLAVINS 282 Modifications Found on the Ribityl Sidechain 282 Modifications Found on the Flavin Ring 283 Chemical and. Biological Degradation Products •...... 286 TRANSPORT AND METABOLISM 287 Uptake and E�cretion 287 Association with Binding (Caier) Proteins 288 Conversion to Coenzymatic Forms 290 COENZYME BINDING BY APOFLA VOPROTEINS ....... 292 INFLUENCE OF NUTRITIONAL STATUS ON FLAVOPROTEINS .. ...... 294 FLAVOPROTEIN REACTIONS AND MECHANISMS 296 Survey of F/avoenzymes 296 One-Electron Trans/erases 300 Dehydrogenases 301 Pyridine nuc/eotide-dependent dehydrogenases ... ......... ........ 301 Non-pyridine nucleotide-dependent dehydrogenases 302 Complex jlavoproteins 303 Pyridine nucleotide-disulftde oxidoreductases 304 Dehydrogenase/O�ygen Reductase Enzymes 305
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Merrill et al. (1981) studied this question.