What question did this study set out to answer?

Establish multidisciplinary expert recommendations to guide clinicians on evaluating disease severity, assessing treatment outcomes, and integrating newly approved targeted systemic agents into atopic dermatitis management.

September 29, 2017The Journal of Allergy and Clinical Immunology In PracticeOpen Access

Expert Perspectives on Management of Moderate-to-Severe Atopic Dermatitis: A Multidisciplinary Consensus Addressing Current and Emerging Therapies

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Authors

MBMark BoguniewiczNational Jewish Health AAAndrew AlexisCornell University LBLisa A. BeckUniversity of Rochester Medical Center

Discussion

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Implication

Expert consensus outlines clinical recommendations for moderate-to-severe atopic dermatitis, highlighting the integration of targeted systemic therapies and standardized treatment assessment.

Key Points

Establish multidisciplinary expert recommendations to guide clinicians on evaluating disease severity, assessing treatment outcomes, and integrating newly approved targeted systemic agents into atopic dermatitis management.
Convened a multidisciplinary steering committee composed of dermatologists, allergists, and a patient advocacy group representative.
Conducted a targeted literature review and synthesized expert opinion to bridge gaps resulting from delayed updates in national clinical guidelines.
Identified critical shortcomings in standard systemic therapies, noting that systemic steroids are not guideline-supported due to disease rebound and off-label immunosuppressants carry serious adverse risks.
Formulated practical clinical recommendations on incorporating dupilumab for patients uncontrolled by topical therapies and established criteria to define treatment response and failure.

Cite This Study

Boguniewicz et al. (2017) studied this question.

synapsesocial.com/papers/6a79987f8a3ae1c742324cbd https://doi.org/10.1016/j.jaip.2017.08.005

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Implication

Expert consensus outlines clinical recommendations for moderate-to-severe atopic dermatitis, highlighting the integration of targeted systemic therapies and standardized treatment assessment.

Expert Perspectives on Management of Moderate-to-Severe Atopic Dermatitis: A Multidisciplinary Consensus Addressing Current and Emerging Therapies

Discussion

Member takes

Implication

Key Points

Cite This Study

Expert Perspectives on Management of Moderate-to-Severe Atopic Dermatitis: A Multidisciplinary Consensus Addressing Current and Emerging Therapies

Discussion

Member takes

Implication

Key Points

Cite This Study

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