Key result
Physical activity and exercise are effective for improving exercise tolerance, lipid concentrations, blood pressure, and reducing the risk of thrombosis in cardiovascular disease.
Why the study?
Physical inactivity unequivocally contributes to cardiovascular diseases like coronary artery disease and stroke, prompting investigation into how physical activity and exercise influence various health aspects and cardiovascular mechanisms.
Does physical activity and exercise improve cardiovascular health markers and reduce the risk of cardiovascular disease?
Does physical activity and exercise improve cardiovascular health markers and reduce the risk of cardiovascular disease?
This narrative review highlights the multifaceted mechanisms—including telomere preservation, improved endothelial function, and reduced thrombosis risk—by which physical activity acts as medicine for cardiovascular disease.
PA may improve endothelial function, BP, lipids, and thrombosis; leaves open need for prospective trials on dosing.
BACKGROUND: Physical inactivity and resultant lower energy expenditure contribute unequivocally to cardiovascular diseases, such as coronary artery disease and stroke, which are considered major causes of disability and mortality worldwide. AIM: The aim of the study was to investigate the influence of physical activity (PA) and exercise on different aspects of health - genetics, endothelium function, blood pressure, lipid concentrations, glucose intolerance, thrombosis, and self - satisfaction. Materials and. METHODS: In this article, we conducted a narrative review of the influence PA and exercise have on the cardiovascular system, risk factors of cardiovascular diseases, searching the online databases; Web of Science, PubMed and Google Scholar, and, subsequently, discuss possible mechanisms of this action. RESULTS AND DISCUSSION: Based on our narrative review of literature, discussed the effects of PA on telomere length, nitric oxide synthesis, thrombosis risk, blood pressure, serum glucose, cholesterol and triglycerides levels, and indicated possible mechanisms by which physical training may lead to improvement in chronic cardiovascular diseases. CONCLUSION: PA is effective for the improvement of exercise tolerance, lipid concentrations, blood pressure, it may also reduce the serum glucose level and risk of thrombosis, thus should be advocated concomitant to, or in some cases instead of, traditional drug-therapy.
No takes yet. Share an insight, caveat, or question.
Gronek et al. (2020) conducted a review in Cardiovascular disease. Physical activity and exercise vs. Sedentary lifestyle or traditional drug therapy was evaluated. Physical activity and exercise are effective for improving exercise tolerance, lipid concentrations, blood pressure, and reducing the risk of thrombosis in cardiovascular disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: