Why the study?
Does peroral glucose or corn oil alter adipose tissue lipoprotein lipase activity and plasma lipid/insulin levels in fasting healthy volunteers?
Does peroral glucose or corn oil alter adipose tissue lipoprotein lipase activity and plasma lipid/insulin levels in fasting healthy volunteers?
Carbohydrate intake rapidly stimulates adipose tissue lipoprotein lipase activity and suppresses lipolysis, whereas lipid intake does not acutely affect these parameters.
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Acute glucose effects on adipose LPL seen in healthy volunteers warrant no practice change; leaves open extension to metabolic disease states.
Glucose or corn oil was given perorally to fasting, young healthy volunteers, and the time course of acute effects on lipoprotein lipase activity (LLA) in adipose tissue, plasma glycerol, triglyceride, insulin, and blood glucose levels was followed. After glucose intake, adipose tissue LLA increased rapidly, reaching a maximum of 80 per cent above initial level after 2 h. Plasma glycerol, reflecting the rate of lipolysis of depot lipids, decreased rapidly, temporally well correlated to the LLA changes. After corn oil intake no significant effect on any of the parameters studied was observed except for an increase in the plasma triglyceride level caused by the influx of dietary lipid.
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Nilsson‐Ehle et al. (1975) studied this question.
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