Key result
Treatment with levothyroxine and standard heart failure therapy led to normalization of left ventricular function (EF: 55%) and absence of tachyarrhythmias at 6 months.
Why the study?
Hypothyroidism is typically associated with bradyarrhythmias, but can rarely precipitate life-threatening ventricular arrhythmias.
Design
Case report
Follow-up
6 months
Authors
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Hypothyroidism may rarely trigger polymorphic VT; Level 5 case report leaves association hypothesis-generating.
Case Report (n=1)
Severe hypothyroidism can rarely present as life-threatening polymorphic ventricular tachycardia and reversible left ventricular dysfunction, which resolves with thyroid hormone replacement and standard heart failure therapy.
Waddankeri et al. (2025) conducted a case report in Severe hypothyroidism manifesting as polymorphic ventricular tachycardia (n=1). Levothyroxine and standard heart failure therapy was evaluated on Resolution of symptoms, tachyarrhythmias, and normalization of LV function. Treatment with levothyroxine and standard heart failure therapy led to normalization of left ventricular function (EF: 55%) and absence of tachyarrhythmias at 6 months.
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