Key result
COVID-19 vaccination was temporally associated with the development of acute myocarditis, with symptoms typically onsetting a median of 3 days post-vaccination.
Why the study?
COVID-19 vaccination related adverse events is an evolving field.
Does COVID-19 vaccination cause acute myocardial injury or myocarditis?
Case Report (n=38)
Does COVID-19 vaccination cause acute myocardial injury or myocarditis?
COVID-19 vaccination, particularly the second dose, may be associated with a rare risk of acute myocardial injury or myocarditis, necessitating vigilance among physicians.
Case reports of temporal association warrant clinical vigilance but should not alter vaccination practice; leaves open causality and incidence for controlled studies.
COVID-19 vaccination related adverse events is an evolving field. Here we present a case of acute myocardial injury that developed as a result of an acute immune response following the second dose of COVID-19 vaccination (Moderna) in a 67-year-old man who presented in acute congestive heart failure. His clinical course improved over 3 days. Review of the Vaccine Adverse Events Reporting System (VAERS) in the Centers for Disease Control and Prevention websites identified 37 vaccine recipients who developed myocarditis as an adverse event following COVID-19 vaccination. With the mass expansion of COVID-19 vaccine administration, physicians need to be vigilant about the possibility of new adverse events.
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Deb et al. (2021) conducted a case report in Acute myocardial injury / Myocarditis (n=38). COVID-19 vaccination was evaluated on Development of myocarditis following vaccination. COVID-19 vaccination was temporally associated with the development of acute myocarditis, with symptoms typically onsetting a median of 3 days post-vaccination.
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