Key result
Surgical excision of a large primary retroperitoneal synovial sarcoma followed by adjuvant radiotherapy resulted in no signs of relapse at 60 months of follow-up.
Why the study?
Synovial sarcoma usually develops from areas with synovial tissue such as the extremities, but several cases of retroperitoneal synovial sarcoma have been described.
Case Report (n=1)
Retroperitoneal synovial sarcoma is a rare tumor that requires complete histological examination including immunochemistry and genetic analysis for final diagnosis.
Supports multimodal therapy in rare retroperitoneal synovial sarcomas; leaves open optimal strategies pending prospective validation.
BACKGROUND: Synovial sarcoma (SS) is a rare type of soft tissue sarcoma that is usually developed from areas where synovial tissue exists, especially at the extremities. Nevertheless, several cases of retroperitoneal SS (RSS) have been described. We herein report a case of RSS presented in our institution. CASE SUMMARY: A 69-year-old female patient was admitted with a large, palpable, firm mass in the right abdominal space SS. Computerized tomography scan depicted a concentric, sharply marinated retro-peritoneal lesion which was displacing the right kidney and the lower edge of the liver. Subsequently, the patient underwent surgical excision of the mass with additional right nephrectomy and resection of the right adrenal gland and a part of the diaphragm. The final histological diagnosis of the tumour was grade II monophasic RSS. CONCLUSION: RSS is encountered in the biphasic type, the monophasic fibrous, and the monophasic epithelial category as well. Relevant clinical manifestations are not always documented at early stages. Therefore, the final diagnosis is posed after complete histological examination taking into consideration the results of immunochemistry and genetic analysis. Therapeutic approach happens often late when metastases at the lungs and the liver are apparent. Thus, 5-year survival rates remain low.
No takes yet. Share an insight, caveat, or question.
Mastoraki et al. (2019) conducted a case report in Primary retroperitoneal synovial sarcoma (n=1). Surgical excision and adjuvant radiotherapy was evaluated on Recurrence-free survival. Surgical excision of a large primary retroperitoneal synovial sarcoma followed by adjuvant radiotherapy resulted in no signs of relapse at 60 months of follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: