Key result
COVID-19 was associated with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque in a case series of three patients.
COVID-19 may precipitate acute ischemic stroke through a novel mechanism of fulminant carotid atherothrombosis overlying mild plaque, driven by endotheliitis and coagulopathy.
May signal distinct COVID-19 stroke mechanism via carotid thrombosis; hypothesis-generating and requires prospective validation.
We present a radiology-pathology case series of 3 patients with coronavirus disease 2019 (COVID-19) with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque and propose a novel stroke mechanism: COVID-associated carotid atherothrombosis.
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Esenwa et al. (2020) studied this question. COVID-19 was associated with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque in a case series of three patients.
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