Key result
Metabolic syndrome and insulin resistance in childhood are driven by lipid deposition in insulin-responsive tissues, inducing systemic inflammation and requiring careful risk stratification.
Population
Obese children and adolescents
Design
Review
Authors
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Ectopic lipid deposition may drive pediatric insulin resistance; leaves open targeted interventions in metabolic syndrome.
This review highlights the pathophysiology of metabolic syndrome in children and emphasizes the role of basic clinical evaluation for risk stratification in pediatric obesity.
Ighbariya et al. (2018) conducted a review in Metabolic syndrome and insulin resistance in children. Metabolic syndrome and insulin resistance in childhood are driven by lipid deposition in insulin-responsive tissues, inducing systemic inflammation and requiring careful risk stratification.
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