Key result
Octogenarians undergoing coronary artery bypass grafting had a significantly higher risk of mortality (OR 1.41) and postoperative complications compared to septuagenarians.
Why the study?
As the population ages and more older patients undergo cardiac surgery, the impact of age on postoperative outcomes following CABG remains to be assessed.
Does advanced age (80-89 years vs 70-79 years) and female gender worsen postoperative outcomes and mortality in older patients undergoing CABG?
Observational (n=67,568)
Yes
Does advanced age (80-89 years vs 70-79 years) and female gender worsen postoperative outcomes and mortality in older patients undergoing CABG?
Odds Ratio: 1.41 (95% CI 1.36–1.61)
p-value: p=<0.001
Octogenarians, particularly females, face significantly higher risks of postoperative complications and mortality following CABG compared to septuagenarians, highlighting the need for careful patient selection and consideration of less invasive alternatives like PCI.
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May inform preoperative counseling for octogenarians; leaves open whether optimized care mitigates excess risk.
Lemaire et al. (2020) conducted an observational in Coronary artery disease requiring CABG (n=67,568). Age 80-89 years (Octogenarians) vs. Age 70-79 years (Septuagenarians) was evaluated on Mortality (OR 1.41, 95% CI 1.36-1.61, p=<0.001). Octogenarians undergoing coronary artery bypass grafting had a significantly higher risk of mortality (OR 1.41) and postoperative complications compared to septuagenarians.
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