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June 19, 2017Tanzania Medical JournalOpen Access

Prevalence and Predictors of Renal Dysfunction among Adult Hypertensive Patients Attending Medical Clinic in North-western Tanzania: A Cross Sectional Study

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Population

360 adult hypertensive patients attending a medical outpatient clinic at Bugando Medical Centre in…

Design

Cross-sectional

Key result

Renal dysfunction was highly prevalent, affecting 53.9% of non-diabetic hypertensive outpatients, with obesity, older age, female gender, high systolic blood pressure, and non-ACEI/ARB use identified as strong predictors.

Authors

ASAnthony SangareSKSamuel KalluvyaRKRodrick Kabangila

Discussion

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Overview

High prevalence supports renal screening consideration in non-diabetic hypertensives; hypothesis-generating for targeted interventions in African cohorts.

Study Design

Type

Cross-Sectional (n=360)

Multicenter

No

Structured PICO

P
Population
360 non-diabetic adult hypertensive outpatients in Tanzania were evaluated for the prevalence and predictors of renal dysfunction.
O
Outcome
Renal dysfunction defined as an estimated glomerular filtration rate (eGFR) < 90ml/min/1.73m2 (calculated using the Cockroft-Gault equation) and/or the presence of albuminuria.surrogate

Renal dysfunction is highly prevalent (53.9%) among non-diabetic hypertensive outpatients in North-western Tanzania, highlighting the critical need for routine renal function monitoring in this population.

Limitations

  • Single centre, clinic-based study limiting generalizability
  • Relatively small sample size
  • Renal biopsy was not performed
  • Lack of screening for Schistosomiasis and hepatitis C
  • APOL 1 risk allele was not tested
  • Renal biopsy (gold standard) was not performed
  • Lack of screening for Schistosomiasis, hepatitis C, and APOL 1 risk allele

Cite This Study

Sangare et al. (2017) conducted a cross-sectional in Hypertension (n=360). Hypertension was evaluated on Renal dysfunction (eGFR < 90ml/min/1.73m2 and/or presence of albuminuria). Renal dysfunction was highly prevalent, affecting 53.9% of non-diabetic hypertensive outpatients, with obesity, older age, female gender, high systolic blood pressure, and non-ACEI/ARB use identified as strong predictors.

synapsesocial.com/papers/6a79d72a77336a1bae028311https://doi.org/10.4314/tmj.v29i1.264
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