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July 1, 1994CirculationOpen Access

Optimal blood pressure control in treated hypertensive patients. Report from the Department of Health Hypertension Care Computing Project (DHCCP).

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Why the study?

What is the optimal range of treated systolic and diastolic blood pressure associated with the best survival in hypertensive patients?

Population

6,214 treated hypertensive patients with an average age of 52 years, enrolled in the Department of Health…

Design

Cohort

Follow-up

mean 107 months

Authors

CBC J BulpittAPAndrew PalmerAFAstrid Fletcher

Discussion

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Member takes

Overview

May support sex-specific SBP and DBP <95 mm Hg targets; hypothesis-generating and leaves optimal thresholds open for RCTs.

Structured PICO

What is the optimal range of treated systolic and diastolic blood pressure associated with the best survival in hypertensive patients?

P
Population
6,214 treated hypertensive patients (3,070 men and 3,144 women) with an average age of 52 years, enrolled in the Department of Health Hypertension Care Computing Project (DHCCP) across 5 specialist clinics and general practitioners.
I
Intervention
Achieved treated systolic and diastolic blood pressure levels
O
Outcome
Total, cardiovascular, ischemic heart disease (IHD), and stroke mortalityhard clinical

In treated hypertensive patients, optimal survival is associated with achieving a systolic blood pressure <134 mm Hg in men and <149 mm Hg in women, and a diastolic blood pressure <95 mm Hg.

Cite This Study

Bulpitt et al. (1994) studied this question.

synapsesocial.com/papers/6a79ddeae357fbdac58940b0https://doi.org/10.1161/01.cir.90.1.225
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treated blood pressure, rather than pretreatment, predicts survival in hypertensive patients A report from the DHSS Hypertension Care Computing Project (DHCCP)1988 · 18 citations
  2. 2Prognostic Value of Systolic and Diastolic Blood Pressure in Treated Hypertensive Men2002 · 176 citations
  3. 3Relation between treated blood pressure and death from ischaemic heart disease at different ages: a report from the Department of Health Hypertension Care Computing Project1992 · 8 citations
  4. 4Outcomes of Treated Hypertension at Age 80 and Older: Cohort Analysis of 79,376 Individuals2016 · 43 citations
  5. 5Mortality implications of lower DBP with lower achieved systolic pressures in coronary artery disease2017 · 6 citations