Why the study?
Does treated blood pressure level correlate with ischaemic heart disease mortality differently across age groups in hypertensive patients?
Population
6216 hypertensive patients (2250 men and 2126 women aged < 60 years; 822 men and 1018 women aged >= 60 years)
Design
Cohort
Follow-up
mean 107 months
Key result
The positive relation between treated diastolic blood pressure and IHD mortality decreased with age, while the relative hazard rate for systolic blood pressure remained positive (1.008-1.021).
Authors
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Treated diastolic BP–IHD mortality link weakens with age while systolic persists; leaves open age-specific targets in hypertension.
Cohort (n=6,216)
Yes
Does treated blood pressure level correlate with ischaemic heart disease mortality differently across age groups in hypertensive patients?
Effect estimate: RHR 1.008-1.021
The positive relationship between treated diastolic blood pressure and ischemic heart disease mortality decreases with age, whereas the relationship with systolic blood pressure persists in older patients.
Bulpitt et al. (1992) conducted a cohort in Hypertension (n=6,216). Treated blood pressure vs. Lower treated blood pressure was evaluated on Mortality from ischaemic heart disease (RHR 1.008-1.021). The positive relation between treated diastolic blood pressure and IHD mortality decreased with age, while the relative hazard rate for systolic blood pressure remained positive (1.008-1.021).