Why the study?
Does active antihypertensive treatment alter the relationship between treated blood pressure and mortality in elderly patients with hypertension?
Does active antihypertensive treatment alter the relationship between treated blood pressure and mortality in elderly patients with hypertension?
In elderly hypertensive patients, mortality has a U-shaped or inverse relationship with treated blood pressure, suggesting that the lowest achieved blood pressures may be associated with increased mortality and deteriorating general health.
Answers are grounded in this paper and cite their sources.
Supports caution against very low achieved BPs in elderly hypertensives; extends J-curve evidence from active-treatment arms.
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Staessen et al. (1989) studied this question.
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