Key result
Patients hospitalized with heart failure who were comfortable at rest but breathless on slight exertion had higher 180-day mortality than those short of breath at rest (34% vs 19%; OR 2.29).
Why the study?
Does presentation with CARBOSE compared to SOBAR predict worse mortality in patients hospitalized with heart failure?
Observational (n=311)
Does presentation with CARBOSE compared to SOBAR predict worse mortality in patients hospitalized with heart failure?
Odds Ratio: 2.29 (95% CI 1.29–4.06)
Absolute Event Rate: 34% vs 19%
p-value: p=0.005
Patients hospitalized with heart failure who are comfortable at rest but breathless on slight exertion (CARBOSE) represent the majority of admissions and have a worse 180-day prognosis than those who are short of breath at rest.
Authors
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CARBOSE presentation may flag higher-risk HF inpatients for closer follow-up; leaves open whether dyspnea grading improves existing risk models.
Shoaib et al. (2014) conducted an observational in Heart failure (n=311). Comfortable at rest but breathless on slight exertion (CARBOSE) vs. Short of breath at rest (SOBAR) was evaluated on 180-day mortality (OR 2.29, 95% CI 1.29-4.06, p=0.005). Patients hospitalized with heart failure who were comfortable at rest but breathless on slight exertion had higher 180-day mortality than those short of breath at rest (34% vs 19%; OR 2.29).
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