Population
Healthy young and elderly subjects, and individuals aged > 65 years with 'ageing-related' orthostatic…
Design
Review
Authors
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May inform orthostatic hypotension management by targeting central baroreflex pathways; extends mechanistic insights but remains hypothesis-generating pending trials.
Ageing-related orthostatic hypotension is primarily driven by changes in the central connections of the arterial baroreflex, rather than efferent limb impairment or arterial compliance.
Wing et al. (1997) studied this question.
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