Key result
Hypertension in elderly subjects was associated with a greater maximum fall in systolic blood pressure during orthostasis compared to normotensive controls (45 vs 29 mmHg, P=0.04).
Why the study?
Is postural change in blood pressure related to baroreflex sensitivity in elderly subjects, independent of baseline blood pressure?
Cross-Sectional (n=25)
Is postural change in blood pressure related to baroreflex sensitivity in elderly subjects, independent of baseline blood pressure?
Absolute Event Rate: 45% vs 29%
p-value: p=0.04
In elderly subjects, reduced baroreflex sensitivity is associated with greater postural falls in systolic blood pressure, particularly in those with hypertension.
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May warrant orthostatic monitoring in hypertensive elderly; leaves open baroreflex mediation independent of baseline BP.
Martin James (1999) conducted a cross-sectional in Hypertension (n=25). Hypertension vs. Normotensive controls was evaluated on Maximum change in systolic blood pressure with orthostasis (p=0.04). Hypertension in elderly subjects was associated with a greater maximum fall in systolic blood pressure during orthostasis compared to normotensive controls (45 vs 29 mmHg, P=0.04).
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