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March 17, 2018Canadian Journal of CardiologyOpen Access

Prevalence and Clinical Correlates of Sleep-Disordered Breathing in Patients Hospitalized With Acute Decompensated Heart Failure

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Why the study?

What is the prevalence and what are the clinical correlates of sleep-disordered breathing in patients hospitalized with acute decompensated heart failure and LV systolic dysfunction?

Population

105 consecutive patients with LV ejection fraction < 50% hospitalized with acute decompensated heart failure

Design

Cross-sectional

Key result

Sleep-disordered breathing was present in 67% of patients hospitalized with acute decompensated heart failure and left ventricular systolic dysfunction, and was significantly correlated with high BMI and elevated left ventricular filling pressure.

Authors

SSShoko SudaTKTakatoshi KasaiHMHiroki Matsumoto

Discussion

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Overview

SDB common in ADHF with LV dysfunction; leaves open whether polysomnography-guided therapy improves outcomes.

Study Design

Type

Cross-Sectional

Structured PICO

What is the prevalence and what are the clinical correlates of sleep-disordered breathing in patients hospitalized with acute decompensated heart failure and LV systolic dysfunction?

P
Population
Hospitalized patients with acute decompensated heart failure and left ventricular systolic dysfunction evaluated for sleep-disordered breathing using polysomnography.
O
Outcome
Prevalence of sleep-disordered breathing (SDB) assessed by apnea-hypopnea index (AHI) and its clinical correlates

Sleep-disordered breathing, particularly central sleep apnea, is highly prevalent in patients hospitalized with acute decompensated heart failure and correlates with elevated filling pressures (E/e') and loop diuretic use.

Cite This Study

Suda et al. (2018) conducted a cross-sectional in Acute decompensated heart failure with left ventricular systolic dysfunction. Sleep-disordered breathing was evaluated on Prevalence of sleep-disordered breathing. Sleep-disordered breathing was present in 67% of patients hospitalized with acute decompensated heart failure and left ventricular systolic dysfunction, and was significantly correlated with high BMI and elevated left ventricular filling pressure.

synapsesocial.com/papers/6a79f2ae8a3ae1c7423280c1https://doi.org/10.1016/j.cjca.2018.03.006
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