Key result
The oral contraceptive Estrostep caused severe hypertriglyceridemia (2,200 mg/dL) and acute pancreatitis in a 24-year-old woman after nearly 10 years of use.
Case Report (n=1)
This case highlights that long-term use of norethindrone acetate/ethinyl estradiol can rarely cause severe hypertriglyceridemia-induced acute pancreatitis.
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Alerts clinicians to rare pancreatitis risk in long-term norethindrone/ethinyl estradiol users; hypothesis-generating and should not change practice.
Abraham et al. (2014) conducted a case report in Severe hypertriglyceridemia-induced acute pancreatitis (n=1). Norethindrone acetate/ethinyl estradiol (Estrostep) was evaluated on Severe hypertriglyceridemia-induced acute pancreatitis. The oral contraceptive Estrostep caused severe hypertriglyceridemia (2,200 mg/dL) and acute pancreatitis in a 24-year-old woman after nearly 10 years of use.
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