Why the study?
Is the HindIII restriction fragment length polymorphism of the lipoprotein lipase gene associated with unfavorable lipid levels and increased risk of myocardial infarction?
Population
2,520 individuals, comprising 1,361 participants from a general population survey and 1,159 patients with…
Comparison
HindIII restriction fragment length polymorphism… vs Other genotypes
Design
Case-control
Authors
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H2H2 genotype links to adverse lipids without higher prior MI prevalence; leaves open LPL polymorphism's role in risk prediction.
Is the HindIII restriction fragment length polymorphism of the lipoprotein lipase gene associated with unfavorable lipid levels and increased risk of myocardial infarction?
Although the H2H2 genotype of the lipoprotein lipase gene is associated with unfavorable lipid levels, it does not significantly increase the risk of myocardial infarction.
Stephan Holmer (2000) studied this question.
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