Key result
Nonalcoholic steatohepatitis was associated with increased left ventricular mass index (82.6 vs 78.6 g/m2; adjusted ß=7.16, P=0.001) and left atrial volume index, suggesting subclinical heart failure.
Why the study?
Is nonalcoholic steatohepatitis associated with echocardiographic changes in cardiac structure and function in patients undergoing bariatric surgery?
Population
65 individuals without known heart disease undergoing elective bariatric surgery with perioperative liver…
Comparison
Nonalcoholic steatohepatitis diagnosed via… vs Without NASH
Design
Cohort
Authors
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Does not support routine cardiac screening in NASH; hypothesis-generating for subclinical HF links needing prospective validation.
Cohort (n=65)
Is nonalcoholic steatohepatitis associated with echocardiographic changes in cardiac structure and function in patients undergoing bariatric surgery?
Mean Difference: 7.16
Absolute Event Rate: 82.6% vs 78.6%
p-value: p=0.001
NASH is associated with subclinical changes in myocardial structure and diastolic function, suggesting an early link to heart failure.
Simon et al. (2017) conducted a cohort in Nonalcoholic steatohepatitis (n=65). Nonalcoholic steatohepatitis vs. Without nonalcoholic steatohepatitis was evaluated on Left ventricular mass index (ß 7.16, p=0.001). Nonalcoholic steatohepatitis was associated with increased left ventricular mass index (82.6 vs 78.6 g/m2; adjusted ß=7.16, P=0.001) and left atrial volume index, suggesting subclinical heart failure.
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