Key result
Serum retinol-binding protein 4 concentrations were inversely associated with carotid artery intima-media echogenicity (beta -0.39; 95% CI -0.55 to -0.22).
Why the study?
Are serum retinol-binding protein 4 (RBP4) levels associated with subclinical cardiovascular disease in 70-year-old adults?
Observational (n=1,008)
Are serum retinol-binding protein 4 (RBP4) levels associated with subclinical cardiovascular disease in 70-year-old adults?
Effect estimate: beta -0.39 (95% CI -0.55 to -0.22)
Circulating RBP4 concentrations are inversely associated with carotid artery intima-media and plaque echogenicity, suggesting a potential role in the development of atherosclerosis.
May inform adipokine research on vascular imaging; leaves open any clinical role in older adults' CVD risk assessment.
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Ingelsson et al. (2008) conducted an observational in Subclinical cardiovascular disease (n=1,008). Serum retinol-binding protein 4 (RBP4) was evaluated on Carotid artery intima-media echogenicity (gray scale median) (beta -0.39, 95% CI -0.55 to -0.22). Serum retinol-binding protein 4 concentrations were inversely associated with carotid artery intima-media echogenicity (beta -0.39; 95% CI -0.55 to -0.22).
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