Why the study?
Is the extent of coronary artery disease associated with the severity of hyperlipoproteinaemia in male patients?
Is the extent of coronary artery disease associated with the severity of hyperlipoproteinaemia in male patients?
The study demonstrates a significant positive correlation between the extent of coronary artery disease and the severity of hyperlipoproteinaemia, particularly in younger male patients.
Lipoprotein analyses were performed in 133 male patients and were correlated with the coronary arteriographic findings. The prevalence of hyperlipoproteinaemia was significantly higher in those patients with coronary artery disease (P less than 0-02). In addition, the more extensive the degree of coronary artery pathology the higher were the plasma concentrations of total cholesterol, triglyceride, and low density lipoprotein (LDL) cholesterol. Hyperlipoproteinaemia was more prevalent in the younger patients with coronary artery disease (P less than 0-02).
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Murray et al. (1975) studied this question.
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