Key result
Capillary blood high-sensitivity troponin analysis via the Atellica VTLi point-of-care analyzer showed equivalent results to venous plasma, with a constant bias of 7.1%.
Why the study?
Differentiating between low-risk and high-risk patients with acute coronary syndrome remains a diagnostic challenge, and point-of-care testing can contribute to earlier disposition decisions.
Does point-of-care high-sensitivity troponin-I analysis in capillary blood provide equivalent results to venous blood and central lab analysis in patients with acute chest pain?
Cross-Sectional (n=152)
Does point-of-care high-sensitivity troponin-I analysis in capillary blood provide equivalent results to venous blood and central lab analysis in patients with acute chest pain?
Effect estimate: 7.1% constant bias
Point-of-care high-sensitivity troponin-I testing using capillary blood provides equivalent results to central laboratory testing, potentially enabling rapid pre-hospital ACS rule-out.
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May support earlier ACS disposition via POC hs-troponin; leaves open outcome impact before practice change.
Bruinen et al. (2022) conducted a cross-sectional in Acute chest pain (n=152). Capillary blood high-sensitivity troponin analysis via Atellica VTLi vs. Venous whole blood and plasma via central lab immunoassay was evaluated on Difference between capillary blood and venous blood/plasma (7.1% constant bias). Capillary blood high-sensitivity troponin analysis via the Atellica VTLi point-of-care analyzer showed equivalent results to venous plasma, with a constant bias of 7.1%.
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