July 4, 2006Annals of Internal Medicine
C-Reactive Protein and Cardiovascular Disease Risk: Still an Unknown Quantity?
Key result
C-reactive protein may not be causally related to coronary heart disease, and its addition to predictive models offers only modest improvements over conventional risk factors.
Design
Editorial
Authors
Discussion
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Member takes
Implication
This editorial highlights the uncertainty regarding the causal role of CRP in cardiovascular disease and questions the clinical utility of adding CRP to standard risk prediction models.
PICO
P
Population
Cardiovascular disease
E
Exposure / Comparator
C-reactive protein
This editorial highlights the uncertainty regarding the causal role of CRP in cardiovascular disease and questions the clinical utility of adding CRP to standard risk prediction models.
Cite This Study
Smith et al. (2006) conducted an editorial in Cardiovascular disease. C-reactive protein was evaluated. C-reactive protein may not be causally related to coronary heart disease, and its addition to predictive models offers only modest improvements over conventional risk factors.