Key result
Overall adherence to the American Society of Health-System Pharmacists guidelines for surgical antimicrobial prophylaxis was 0% across all evaluated parameters in patients undergoing major surgery.
Why the study?
Appropriate surgical antimicrobial prophylaxis prevents surgical site infections, while inappropriate use risks antimicrobial resistance, side effects, and increased cost, motivating an evaluation against standard guidelines.
Population
105 patients who undergone major surgical procedure
Comparison
Surgical antimicrobial prophylaxis use vs standard guideline
Design
Prospective observational study
Follow-up
Daily before, during and after operation till discharge
Authors
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Local SAP practices at this Ethiopian hospital deviate from guidelines; leaves open whether stewardship improves outcomes or curbs resistance.
Observational (n=105)
No
Adherence to international guidelines for surgical antimicrobial prophylaxis in this Ethiopian referral hospital was extremely poor, highlighting a critical need for local guidelines and antimicrobial stewardship.
Tamrat et al. (2018) conducted an observational in Major surgical procedures (n=105). Surgical antimicrobial prophylaxis vs. ASHP guideline standards was evaluated on Overall adherence to American Society of Health-System Pharmacists (ASHP) guidelines for surgical antimicrobial prophylaxis. Overall adherence to the American Society of Health-System Pharmacists guidelines for surgical antimicrobial prophylaxis was 0% across all evaluated parameters in patients undergoing major surgery.
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