February 17, 2004Circulation
Mechanisms of Myocardial Capture and Temporal Excitable Gap During Spiral Wave Reentry in a Bidomain Model
Population
Bidomain sheet model for single spiral wave capture
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Advances mechanistic insights into reentry capture; leaves open translation to human defibrillation.
Structured PICO
P
Population
Bidomain sheet model for single spiral wave capture
I
Intervention
Unipolar stimuli of strengths 4, 8, 16, and 24 mA and 2-ms duration delivered at 99 locations
O
Outcome
Mechanism of myocardial capture and spatial distribution of temporal excitable gap
In a bidomain model of spiral wave reentry, cathode-break excitation is the dominant mechanism of myocardial capture, providing mechanistic insights into cardiac fibrillation.
Cite This Study
Ashihara et al. (2004) studied this question.