Key result
Rapid pacing of electrically induced atrial fibrillation in conscious dogs achieved regional capture with a local capture area diameter of 6.1 +/- 1.6 cm and a time window of 12 +/- 4 msec.
Why the study?
Does rapid pacing allow regional control of electrically induced atrial fibrillation in conscious dogs?
Population
5 chronically instrumented conscious dogs with sustained electrically induced atrial fibrillation
Design
Preclinical
Authors
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Regional capture shown in dogs warrants no practice change; leaves open translation to human AF termination strategies.
Does rapid pacing allow regional control of electrically induced atrial fibrillation in conscious dogs?
Rapid pacing can achieve regional control of atrial fibrillation in conscious dogs, demonstrating the presence of a short excitable gap during fibrillation.
Allessie et al. (1991) studied Sustained electrically induced atrial fibrillation (n=5). Rapid pacing (overdrive pacing) was evaluated on Regional capture of the fibrillatory process. Rapid pacing of electrically induced atrial fibrillation in conscious dogs achieved regional capture with a local capture area diameter of 6.1 +/- 1.6 cm and a time window of 12 +/- 4 msec.
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