Key result
High-density mapping in a canine heart failure model demonstrated that sustained atrial fibrillation is characterized by single and multiple stable atrial drivers predominantly in the pulmonary veins and high right atrium.
In a canine model of pacing-induced heart failure, sustained atrial fibrillation is characterized by stable left and right atrial drivers predominantly located in the pulmonary veins and high right atrium.
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Hypothesis-generating for stable driver ablation in HF-associated AF; human studies required before clinical translation.
Ryu et al. (2005) studied Congestive heart failure with sustained atrial fibrillation (n=12). High-density mapping of atrial fibrillation was evaluated on Atrial fibrillation mechanisms based on Fast Fourier Transform analysis and activation sequence mapping. High-density mapping in a canine heart failure model demonstrated that sustained atrial fibrillation is characterized by single and multiple stable atrial drivers predominantly in the pulmonary veins and high right atrium.
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