Carotid baroreflex regulation of sympathetic nerve activity during dynamic exercise in humans

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Why the study?

Does dynamic exercise alter carotid baroreflex control of muscle sympathetic nerve activity in humans?

Structured PICO

Does dynamic exercise alter carotid baroreflex control of muscle sympathetic nerve activity in humans?

Population

8 humans (5 men, 3 women), mean age 23.8 +/- 0.7 years

Intervention

20 min of arm cycling at 50% peak O2 uptake with 5-s periods of neck pressure and neck suction (+45 to -80 Torr)

Comparator

Rest with identical neck pressure and suction

Outcome

Carotid baroreflex (CBR) control of muscle sympathetic nerve activity (MSNA)surrogate

Carotid baroreflex control of sympathetic nerve activity appears to be preserved during moderate-intensity dynamic exercise.

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Supports preserved carotid baroreflex-MSNA control during moderate exercise; leaves open extension to higher intensities or disease states.

Fadel et al. (2001) studied this question.

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Supports preserved carotid baroreflex-MSNA control during moderate exercise; leaves open extension to higher intensities or disease states.