Population
10,798 participants in 3,320 families recruited as part of the Family Blood Pressure Program
Design
Cross-sectional
Authors
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No immediate clinical implications for hypertension management; leaves open replication and causal variant identification in prospective studies.
Genome-wide linkage analysis identified multiple loci across different chromosomes associated with pulse pressure, supporting a genetic basis for this cardiovascular risk factor.
Bielinski et al. (2005) studied this question.
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