Why the study?
Does trimetazidine improve exercise testing parameters in patients with microvascular angina?
Population
35 patients with microvascular angina, mean age 43.9 +/- 6.4 years (range 36-57), 8 men and 27 women.
Comparison
Trimetazidine 60 mg daily for a 4-week treatment… vs Placebo for a 4-week treatment period
Design
RCT, double-blind
Follow-up
4 weeks per treatment period
Authors
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Supports trimetazidine for microvascular angina symptom relief; extends anti-ischemic exercise data beyond epicardial CAD.
Does trimetazidine improve exercise testing parameters in patients with microvascular angina?
Trimetazidine improves exercise tolerance and reduces ischemia during exercise in patients with microvascular angina.
Nalbantgil et al. (2005) studied this question.
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