Key result
High admission neutrophil to lymphocyte ratio was associated with significantly higher 3-year mortality compared to low NLR (21.6% vs 3%, P<.001) in patients with NSTEMI and UAP.
Why the study?
Does admission neutrophil to lymphocyte ratio predict 3-year cardiovascular mortality in patients with NSTEMI and UAP?
Population
308 patients with non-ST elevation myocardial infarction and unstable angina pectoris, mean age 59.22 ± 11.93
Comparison
High admission neutrophil to lymphocyte ratio vs Low admission neutrophil to lymphocyte ratio (NLR)
Design
Cohort
Follow-up
up to 3 years
Authors
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May support admission NLR for risk stratification in NSTEMI/UAP; leaves open prospective validation before clinical use.
Cohort (n=308)
Does admission neutrophil to lymphocyte ratio predict 3-year cardiovascular mortality in patients with NSTEMI and UAP?
Effect estimate: AUC 0.86 (95% CI 0.8-0.92)
Absolute Event Rate: 21.6% vs 3%
p-value: p=<.001
Admission neutrophil to lymphocyte ratio is a strong, independent predictor of 3-year cardiovascular mortality in patients with NSTEMI and UAP.
Gül et al. (2012) conducted a cohort in Non-ST elevation myocardial infarction (NSTEMI) and unstable angina pectoris (UAP) (n=308). High neutrophil to lymphocyte ratio (NLR) vs. Low neutrophil to lymphocyte ratio (NLR) was evaluated on 3-year mortality (AUC 0.86, 95% CI 0.8-0.92, p=<.001). High admission neutrophil to lymphocyte ratio was associated with significantly higher 3-year mortality compared to low NLR (21.6% vs 3%, P<.001) in patients with NSTEMI and UAP.
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