Gammaglobulin Treatment And Protection Against Infections

The effect of gammaglobulin treatment on the frequency of relapse of acute otitis in children can be summarized as follows: (1) the risk of a first relapse is on an average about 3 % for untreated patients and about 1.5 % per month for gammaglobulin-treated patients; (2) both for untreated and for treated patients the risk of relapse is greatest about 2 months after the otitis, smallest about 6 months after the otitis, with another maximum about 12 months after the otitis; (3) the risk of a second relapse is on an average about 3 % per month both for treated and for untreated patients; (4) relapses of third and higher order occurred in the untreated but not in the treated patients.