Key result
Qiliqiangxin capsule significantly inhibited cardiac hypertrophy and improved hemodynamics in rats with pressure overload heart failure.
Why the study?
Does Qiliqiangxin capsule inhibit cardiac hypertrophy and improve hemodynamics in a rat model of pressure overload heart failure?
Population
SD rats with pressure overload heart failure induced by ascending aorta constriction to establish a model of…
Design
Preclinical
Follow-up
six weeks
Authors
Loading...
Hypothesis-generating in rat pressure-overload HF; leaves open clinical translation and human trials.
Does Qiliqiangxin capsule inhibit cardiac hypertrophy and improve hemodynamics in a rat model of pressure overload heart failure?
In a rat model of pressure overload heart failure, Qiliqiangxin capsule inhibited cardiac hypertrophy and improved hemodynamics by regulating energy metabolism and protecting mitochondrial function via the AMPK/PGC-1α axis.
Zhang et al. (2013) studied Pressure overload heart failure. Qiliqiangxin capsule (QL) was evaluated on Cardiac hypertrophy and hemodynamics. Qiliqiangxin capsule significantly inhibited cardiac hypertrophy and improved hemodynamics in rats with pressure overload heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: