Why the study?
LGE-CMR can define left atrial anatomy and structural remodelling to facilitate AF ablation, but intra- and inter-observer reproducibility needed assessment.
Are late gadolinium enhancement cardiac magnetic resonance measurements reproducible for detecting left atrial fibrosis in patients undergoing atrial fibrillation ablation?
Population
40 randomly selected LGE-CMR examinations from patients undergoing AF ablation procedures
Comparison
Intra- and inter-observer comparisons across experienced and non-experienced observers
Design
Reproducibility and agreement study
Key result
Late gadolinium enhancement cardiac magnetic resonance measurements of left atrial area, volume, and sphericity index were highly reproducible (coefficient of variation <10% and ICC >0.71).
Authors
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LGE-CMR LA measurements show acceptable reproducibility; leaves open whether findings improve ablation outcomes or patient selection.
Observational (n=40)
Are late gadolinium enhancement cardiac magnetic resonance measurements reproducible for detecting left atrial fibrosis in patients undergoing atrial fibrillation ablation?
LGE-CMR measurements of left atrial parameters and scar location are highly reproducible regardless of observer experience, supporting its use in substrate-based AF ablation.
Mǎrgulescu et al. (2018) conducted an observational in Atrial fibrillation (n=40). Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) was evaluated on Intra- and inter-observer reproducibility of LA volume, LA area, and sphericity index (SI). Late gadolinium enhancement cardiac magnetic resonance measurements of left atrial area, volume, and sphericity index were highly reproducible (coefficient of variation <10% and ICC >0.71).