Key result
Hydroxyethyl starch 130/0.4 resulted in significantly higher preoperative colloid osmotic pressure (p<0.01) and lower postoperative allogeneic blood volumes compared to human albumin.
Why the study?
Does hydroxyethyl starch 130/0.4 improve perioperative hemodynamic parameters compared to human albumin as a priming solution in pediatric congenital heart disease patients undergoing cardiopulmonary bypass surgery?
Cohort
Does hydroxyethyl starch 130/0.4 improve perioperative hemodynamic parameters compared to human albumin as a priming solution in pediatric congenital heart disease patients undergoing cardiopulmonary bypass surgery?
p-value: p=<0.01
Hydroxyethyl starch 130/0.4 may be a viable alternative to human albumin as a priming solution in pediatric patients undergoing relatively simple cardiopulmonary bypass surgeries.
No takes yet. Share an insight, caveat, or question.
May support hydroxyethyl starch as albumin alternative in pediatric CPB; hypothesis-generating and should not yet change practice.
Miao et al. (2014) conducted a cohort in Congenital heart disease. Hydroxyethyl starch 130/0.4 vs. Human albumin was evaluated on Perioperative hemodynamic parameters, renal function, blood loss, allogeneic blood volumes and plasma volume substitution (p=<0.01). Hydroxyethyl starch 130/0.4 resulted in significantly higher preoperative colloid osmotic pressure (p<0.01) and lower postoperative allogeneic blood volumes compared to human albumin.
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