Key result
A cardiopulmonary bypass prime containing two-thirds hydroxyethyl starch ensured an 85% reduction of interstitial fluid relative to Ringer's solution alone, with shorter recovery times.
Why the study?
Does the addition of hydroxyethyl starch to Ringer's solution prime reduce interstitial fluid expansion and improve recovery times in patients undergoing cardiopulmonary bypass?
Population
50 patients undergoing cardiopulmonary bypass
Comparison
Hydroxyethyl starch added to Ringer's solution… vs Ringer's solution alone and preoperative baseline
Design
Other
Follow-up
Perioperative/postoperative
Authors
Loading...
May reduce fluid shifts during bypass; leaves open whether hydroxyethyl starch primes improve outcomes in randomized trials.
Does the addition of hydroxyethyl starch to Ringer's solution prime reduce interstitial fluid expansion and improve recovery times in patients undergoing cardiopulmonary bypass?
Effect estimate: 85% reduction
Using a cardiopulmonary bypass prime composed of two-thirds hydroxyethyl starch and one-third Ringer's solution optimally reduces interstitial fluid expansion and shortens recovery times.
Ali et al. (2004) studied Cardiopulmonary bypass (n=50). Hydroxyethyl starch (HES) vs. Preoperative patients (Group I) and 1:0 Ringer's to HES (Group II) was evaluated on Body fluids expansion, ventilation and recovery time, blood rheologic properties, clotting parameters, platelet counts, blood loss and red blood cell membrane properties (85% reduction). A cardiopulmonary bypass prime containing two-thirds hydroxyethyl starch ensured an 85% reduction of interstitial fluid relative to Ringer's solution alone, with shorter recovery times.
Synapse has enriched one closely related paper. Consider it for comparative context: