Key result
A velocity ratio of 2.5 derived from Vector Flow Imaging significantly distinguished superficial femoral artery stenoses with >50% diameter reduction from non-significant stenoses (AUC 0.79).
Why the study?
Does Vector Flow Imaging (VFI) ultrasound distinguish significant stenoses (>50% diameter reduction) from non-significant stenoses in patients with suspected peripheral arterial disease?
Observational (n=11)
Single-blind (ultrasound analysis blinded to angiographic results)
No
Does Vector Flow Imaging (VFI) ultrasound distinguish significant stenoses (>50% diameter reduction) from non-significant stenoses in patients with suspected peripheral arterial disease?
Vector Flow Imaging (VFI) ultrasound can distinguish significant (>50%) from non-significant stenoses in the superficial femoral artery using a velocity ratio cutoff of 2.5, offering a potential angle-independent alternative to spectral Doppler.
Answers are grounded in this paper and cite their sources.
VFI velocity ratio ≥2.5 may identify significant SFA stenoses; leaves open clinical adoption pending larger prospective validation.
PURPOSE: Atherosclerotic arteries are challenging to evaluate quantitatively using spectral Doppler ultrasound because of the turbulent flow conditions that occur in relation to the atherosclerotic stenoses. Vector velocity ultrasound is angle independent and provides flow information, which could potentially improve the diagnosis of arterial stenoses. The purpose of the study is to distinguish significant stenoses in the superficial femoral artery (> 50% diameter reduction) from non-significant stenoses based on velocity ratios derived from the commercially available vector velocity ultrasound technique Vector Flow Imaging (VFI). MATERIALS AND METHODS: Velocity ratios (intrastenotic blood flow velocity divided by pre- or poststenotic velocity) from a total of 16 atherosclerotic stenoses and plaques in the superficial femoral artery of 11 patients were obtained using VFI. The stenosis degree, expressed as percentage diameter reduction of the artery, was determined from digital subtraction angiography and compared to the velocity ratios. RESULTS: A velocity ratio of 2.5 was found to distinguish clinically relevant stenoses with>50% diameter reduction from clinically non-relevant stenoses with<50% diameter reduction and the difference was statistically significant. CONCLUSION: The study indicates that VFI is a potential future tool for the evaluation of arterial stenoses.
No takes yet. Share an insight, caveat, or question.
Hansen et al. (2018) conducted an observational in Peripheral arterial disease (n=11). Vector Flow Imaging (VFI) velocity ratios vs. Digital subtraction angiography (DSA) was evaluated on Distinguishing >50% vs <50% angiographic diameter reduction using VFI velocity ratios (AUC 0.79, 95% CI 0.46-1, p=0.02). A velocity ratio of 2.5 derived from Vector Flow Imaging significantly distinguished superficial femoral artery stenoses with >50% diameter reduction from non-significant stenoses (AUC 0.79).
Synapse has enriched 10 related papers. Consider them for comparative context: