Why the study?
Does 64 multi-detector CT coronary angiography accurately detect graft patency, occlusion, and stenosis compared to invasive coronary angiography in patients post CABG?
Does 64 multi-detector CT coronary angiography accurately detect graft patency, occlusion, and stenosis compared to invasive coronary angiography in patients post CABG?
64-slice MDCT coronary angiography is a highly sensitive and accurate non-invasive imaging technique for evaluating CABG graft patency and detecting stenosis.
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May support MDCT for post-CABG graft evaluation; leaves open prospective validation versus invasive angiography.
To assess the accuracy of coronary CTA in detection of coronary artery bypass graft patency, occlusion and stenosis. Twenty-four patients with past history of coronary bypass surgery were included in this study and underwent MDCT coronary angiography. Invasive coronary angiography was done within 2 weeks of MDCT coronary angiography. All grafts considered patent were then evaluated for the presence of significant stenosis. Significant stenosis was defined as reduction in diameter of more than 50%. All the MDCT scans were interpretable and a total number of 78 CABG conduits were analyzed. At MDCT angiography 4 (5.2%) grafts were classified as occluded and 74 (94.8%) grafts were patent. Significant stenosis was detected in 7 (9.4%) out of the 74 patent grafts. At invasive coronary angiography; when occlusion and significant stenosis pooled together they were 9 grafts; 4 arterial and 5 venous. All these 9 grafts were detected at MSCT (sensitivity is 100%). In 67 out of 69 grafts occlusion or significant stenosis was correctly ruled out (specificity 97.1%). The diagnostic accuracy of MDCT angiography when compared with invasive angiography was 97.4%. The negative predictive value was 100% and positive predictive value was 81.8%. MDCT coronary angiography is an accurate imaging technique for the evaluation of CABG patency and in detection of graft stenosis and confirms of previous studies using 64 MDCT.
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Monem et al. (2012) studied this question.
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