Recognizing the diverse and unusual non-cardiovascular presentations of POTS in women is crucial to prevent misdiagnosis and delayed treatment.
Emphasizes POTS diagnostic heterogeneity and misdiagnosis risk; leaves open refined criteria and approved therapies.
Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system that is defined by symptoms of orthostatic intolerance. According to the current criteria for adults, currently, POTS is defined as a heart rate increment of 30 beats/minute or more after 10 minutes of standing in the absence of orthostatic hypotension. There is a vast majority that remains misdiagnosed due to the heterogeneity of the disorder. Due to a lack of Food and Drug Administration (FDA) approved therapy, alternative therapies and over the counter medications are used to alleviate the symptoms. This is an uncommon presentation observed primarily in women, as it is more prevalent in females.
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Anjum et al. (2018) studied this question.
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