Key result
Two POTS cases highlight its pathogenesis, pathophysiology, epidemiology, and clinical management.
Case Report (n=2)
This paper provides a clinical overview and case presentations of POTS, highlighting the consensus diagnostic criteria based on heart rate response to standing.
Case reports illustrate POTS diagnostic criteria; leaves open need for prospective validation before practice change.
Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous group of conditions characterised by autonomic dysfunction and an exaggerated sympathetic response to assuming an upright position. Up till recently, it was largely under-recognised as a clinical entity. There is now consensus about the definition of POTS as a greater than 30/min heart rate increase on standing from a supine position (greater than 40/min increase in 12-19-year-old patients) or an absolute heart rate of greater than 120/min within 10 min of standing from a supine position and in the absence of hypotension, arrhythmias, sympathomimetic drugs or other conditions that cause tachycardia. We present two cases of POTS, followed by a discussion of its pathogenesis, pathophysiology, epidemiology and management.
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Sidhu et al. (2013) conducted a case report in Postural orthostatic tachycardia syndrome (POTS) (n=2). Two cases of postural orthostatic tachycardia syndrome (POTS) are presented alongside a discussion of its pathogenesis, pathophysiology, epidemiology, and management.
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